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hematoxylin  (Vector Laboratories)


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    Vector Laboratories hematoxylin
    Overview of ST annotations and differentially expressed pathways in relation to the stage of aSyn pathology in brains of M83 +/+ mice (A) Bubble plot depicting the regionally enriched markers used for delineating 8 ST annotations in sagittal brain sections from M83 +/+ mice. (B and C) Representative low-magnification (4×) panoramic images of a sagittal brain section showing gray matter regions (in B, <t>hematoxylin</t> counterstain) and corresponding spatial map (in C). (D) UMAP plot depicting distinct clustering of ST profiles in annotations, which additionally includes white matter and choroid plexus based on the abundance of regional markers (in 2A; also see ). (E) UMAP plot depicting distinct clustering of ST profiles in relation to the stage of aSyn pathology in brains of M83 +/+ mice. (F) Dot plots depicting gene ontology (GO) of differentially expressed ST profiles in brains of M83 +/+ mice. The plots were generated in the STRING protein interactions database. Also see B, depicting heatmaps for all HALLMARK gene sets by disease stage and in individual regions.
    Hematoxylin, supplied by Vector Laboratories, used in various techniques. Bioz Stars score: 96/100, based on 7594 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/hematoxylin/product/Vector Laboratories
    Average 96 stars, based on 7594 article reviews
    hematoxylin - by Bioz Stars, 2026-04
    96/100 stars

    Images

    1) Product Images from "Spatial transcriptomics reveals the molecular signatures of prodromal and advanced α-synucleinopathy"

    Article Title: Spatial transcriptomics reveals the molecular signatures of prodromal and advanced α-synucleinopathy

    Journal: iScience

    doi: 10.1016/j.isci.2026.114845

    Overview of ST annotations and differentially expressed pathways in relation to the stage of aSyn pathology in brains of M83 +/+ mice (A) Bubble plot depicting the regionally enriched markers used for delineating 8 ST annotations in sagittal brain sections from M83 +/+ mice. (B and C) Representative low-magnification (4×) panoramic images of a sagittal brain section showing gray matter regions (in B, hematoxylin counterstain) and corresponding spatial map (in C). (D) UMAP plot depicting distinct clustering of ST profiles in annotations, which additionally includes white matter and choroid plexus based on the abundance of regional markers (in 2A; also see ). (E) UMAP plot depicting distinct clustering of ST profiles in relation to the stage of aSyn pathology in brains of M83 +/+ mice. (F) Dot plots depicting gene ontology (GO) of differentially expressed ST profiles in brains of M83 +/+ mice. The plots were generated in the STRING protein interactions database. Also see B, depicting heatmaps for all HALLMARK gene sets by disease stage and in individual regions.
    Figure Legend Snippet: Overview of ST annotations and differentially expressed pathways in relation to the stage of aSyn pathology in brains of M83 +/+ mice (A) Bubble plot depicting the regionally enriched markers used for delineating 8 ST annotations in sagittal brain sections from M83 +/+ mice. (B and C) Representative low-magnification (4×) panoramic images of a sagittal brain section showing gray matter regions (in B, hematoxylin counterstain) and corresponding spatial map (in C). (D) UMAP plot depicting distinct clustering of ST profiles in annotations, which additionally includes white matter and choroid plexus based on the abundance of regional markers (in 2A; also see ). (E) UMAP plot depicting distinct clustering of ST profiles in relation to the stage of aSyn pathology in brains of M83 +/+ mice. (F) Dot plots depicting gene ontology (GO) of differentially expressed ST profiles in brains of M83 +/+ mice. The plots were generated in the STRING protein interactions database. Also see B, depicting heatmaps for all HALLMARK gene sets by disease stage and in individual regions.

    Techniques Used: Generated



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    Overview of ST annotations and differentially expressed pathways in relation to the stage of aSyn pathology in brains of M83 +/+ mice (A) Bubble plot depicting the regionally enriched markers used for delineating 8 ST annotations in sagittal brain sections from M83 +/+ mice. (B and C) Representative low-magnification (4×) panoramic images of a sagittal brain section showing gray matter regions (in B, <t>hematoxylin</t> counterstain) and corresponding spatial map (in C). (D) UMAP plot depicting distinct clustering of ST profiles in annotations, which additionally includes white matter and choroid plexus based on the abundance of regional markers (in 2A; also see ). (E) UMAP plot depicting distinct clustering of ST profiles in relation to the stage of aSyn pathology in brains of M83 +/+ mice. (F) Dot plots depicting gene ontology (GO) of differentially expressed ST profiles in brains of M83 +/+ mice. The plots were generated in the STRING protein interactions database. Also see B, depicting heatmaps for all HALLMARK gene sets by disease stage and in individual regions.
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    Overview of ST annotations and differentially expressed pathways in relation to the stage of aSyn pathology in brains of M83 +/+ mice (A) Bubble plot depicting the regionally enriched markers used for delineating 8 ST annotations in sagittal brain sections from M83 +/+ mice. (B and C) Representative low-magnification (4×) panoramic images of a sagittal brain section showing gray matter regions (in B, <t>hematoxylin</t> counterstain) and corresponding spatial map (in C). (D) UMAP plot depicting distinct clustering of ST profiles in annotations, which additionally includes white matter and choroid plexus based on the abundance of regional markers (in 2A; also see ). (E) UMAP plot depicting distinct clustering of ST profiles in relation to the stage of aSyn pathology in brains of M83 +/+ mice. (F) Dot plots depicting gene ontology (GO) of differentially expressed ST profiles in brains of M83 +/+ mice. The plots were generated in the STRING protein interactions database. Also see B, depicting heatmaps for all HALLMARK gene sets by disease stage and in individual regions.
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    Overview of ST annotations and differentially expressed pathways in relation to the stage of aSyn pathology in brains of M83 +/+ mice (A) Bubble plot depicting the regionally enriched markers used for delineating 8 ST annotations in sagittal brain sections from M83 +/+ mice. (B and C) Representative low-magnification (4×) panoramic images of a sagittal brain section showing gray matter regions (in B, <t>hematoxylin</t> counterstain) and corresponding spatial map (in C). (D) UMAP plot depicting distinct clustering of ST profiles in annotations, which additionally includes white matter and choroid plexus based on the abundance of regional markers (in 2A; also see ). (E) UMAP plot depicting distinct clustering of ST profiles in relation to the stage of aSyn pathology in brains of M83 +/+ mice. (F) Dot plots depicting gene ontology (GO) of differentially expressed ST profiles in brains of M83 +/+ mice. The plots were generated in the STRING protein interactions database. Also see B, depicting heatmaps for all HALLMARK gene sets by disease stage and in individual regions.
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    Image Search Results


    Overview of ST annotations and differentially expressed pathways in relation to the stage of aSyn pathology in brains of M83 +/+ mice (A) Bubble plot depicting the regionally enriched markers used for delineating 8 ST annotations in sagittal brain sections from M83 +/+ mice. (B and C) Representative low-magnification (4×) panoramic images of a sagittal brain section showing gray matter regions (in B, hematoxylin counterstain) and corresponding spatial map (in C). (D) UMAP plot depicting distinct clustering of ST profiles in annotations, which additionally includes white matter and choroid plexus based on the abundance of regional markers (in 2A; also see ). (E) UMAP plot depicting distinct clustering of ST profiles in relation to the stage of aSyn pathology in brains of M83 +/+ mice. (F) Dot plots depicting gene ontology (GO) of differentially expressed ST profiles in brains of M83 +/+ mice. The plots were generated in the STRING protein interactions database. Also see B, depicting heatmaps for all HALLMARK gene sets by disease stage and in individual regions.

    Journal: iScience

    Article Title: Spatial transcriptomics reveals the molecular signatures of prodromal and advanced α-synucleinopathy

    doi: 10.1016/j.isci.2026.114845

    Figure Lengend Snippet: Overview of ST annotations and differentially expressed pathways in relation to the stage of aSyn pathology in brains of M83 +/+ mice (A) Bubble plot depicting the regionally enriched markers used for delineating 8 ST annotations in sagittal brain sections from M83 +/+ mice. (B and C) Representative low-magnification (4×) panoramic images of a sagittal brain section showing gray matter regions (in B, hematoxylin counterstain) and corresponding spatial map (in C). (D) UMAP plot depicting distinct clustering of ST profiles in annotations, which additionally includes white matter and choroid plexus based on the abundance of regional markers (in 2A; also see ). (E) UMAP plot depicting distinct clustering of ST profiles in relation to the stage of aSyn pathology in brains of M83 +/+ mice. (F) Dot plots depicting gene ontology (GO) of differentially expressed ST profiles in brains of M83 +/+ mice. The plots were generated in the STRING protein interactions database. Also see B, depicting heatmaps for all HALLMARK gene sets by disease stage and in individual regions.

    Article Snippet: Hematoxylin , Vector Labs , Cat#H-3401.

    Techniques: Generated